Vascular liver diseases: A sex-oriented analysis of the literature

Dig Liver Dis. 2022 Jul 26;S1590-8658(22)00588-6. doi: 10.1016/j.dld.2022.07.005. Online ahead of print.


Vascular liver diseases are an heterogenous group of diseases that collectively represent an important health issue in the field of liver diseases. This narrative review was elaborated by the Special Interest Group (SIG) "Gender in Hepatology" of the Italian Association for the Study of the Liver (AISF). We aimed to review the current knowledge regarding the potential role of biological sex in patients with vascular liver diseases such as splanchnic vein thrombosis, hepatic vein thrombosis, porto-sinusoidal vascular disorder, and hereditary hemorrhagic telangiectasia. As vascular liver diseases commonly affect young individuals, including women in childbearing age, we also included a specific section on the management of pregnancy in these challenging patients.

Keywords: Gender; Portal hypertension; Pregnancy; Sex.

Publication types

  • Review