Chemical constituents from Abies chensiensis and their antifungal activity

J Asian Nat Prod Res. 2023 Apr;25(4):403-409. doi: 10.1080/10286020.2022.2097078. Epub 2022 Aug 3.

Abstract

One new (1) and six known cycloartane triterpenoids (2-7), along with seven reported abietane diterpenoids (8-14), were isolated from the bark of the branches of Abies chensiensis, of which compounds 2-14 were also received for the first time from the genus of Abies. Structural elucidation of all the compounds was carried out by extensive spectroscopic analyses. Additionally, the antifungal activity of isolated compounds 2-13 was evaluated by inhibiting the growth of fungal mycelium. Among them, compounds 8 and 10 demonstrated obvious inhibitory activity against plant pathogens Fusarium avenaceum and Bipolaris sorokiniana.

Keywords: Abies chensiensis; abietane diterpenoid; antifungal activity; cycloartane triterpenoid.

MeSH terms

  • Abies* / chemistry
  • Abietanes / chemistry
  • Antifungal Agents*
  • Molecular Structure

Substances

  • Antifungal Agents
  • Abietanes