Redesigning culturally tailored intervention in the precision health era: Self-management science context

Nurs Outlook. 2022 Sep-Oct;70(5):710-724. doi: 10.1016/j.outlook.2022.05.015. Epub 2022 Aug 4.


Background: Nurse scientists have significantly contributed to health equity and ensuring cultural tailoring of interventions to meet unique needs of individuals. Methodologies for cultural tailoring of self-mangament interventions among marginalized populations have limitedly accommodated intersectionality and group heterogeneity when addressing health needs.

Purpose: Identify methodological limitations in cultural tailoring of interventions among priority populations and issue recommendations on cultural elements that researchers can target to ensure valid cultural tailoring approaches.

Methods: Synthesis of literature on health equity, self-management, and implementation and dissemination research.

Findings: Among priority populations, intersectionality and group heterogeneity has made group-based cultural tailoring approaches less effective in eliciting desirable health outcomes. Precision health methodology could be useful for cultural tailoring of interventions due to the methodology's focus on individual-level tailoring approaches.

Discussion: We offer ways to advance health equity research using precision health approaches in cultural tailoring through targeting unique elements of culture and relevant psychosocial phenotypes.

Keywords: Chronic disease; Cultural tailoring; Precision health; Psychosocial phenotyping; Self-management; Social determinants of health.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Data Collection
  • Health Equity*
  • Humans
  • Precision Medicine
  • Self-Management*