Antibiotic resistance in Enterobacter hormaechei

Int J Antimicrob Agents. 2022 Oct;60(4):106650. doi: 10.1016/j.ijantimicag.2022.106650. Epub 2022 Aug 4.


Enterobacter hormaechei, a member of the Enterobacter cloacae complex, has emerged as an important pathogen in healthcare-associated infections. Advancements in phylogenetic analyses and whole-genome sequencing techniques have led to the identification of E. hormaechei in numerous locations worldwide. The emergence of antibiotic-resistant E. hormaechei isolates, including those that produce extended-spectrum β-lactamases (ESBLs), AmpC β-lactamases and carbapenemases, has been reported worldwide. In this article, we review the different resistance genes of antibiotic-resistant E. hormaechei.

Keywords: Antibiotic resistance; Carbapenemase; ESBL; Enterobacter cloacae complex; Enterobacter hormaechei; β-Lactamase.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / genetics
  • Drug Resistance, Microbial
  • Enterobacter
  • Enterobacter cloacae
  • Enterobacteriaceae Infections* / drug therapy
  • Humans
  • Microbial Sensitivity Tests
  • Phylogeny
  • beta-Lactamases / genetics


  • Anti-Bacterial Agents
  • Bacterial Proteins
  • beta-Lactamases

Supplementary concepts

  • Enterobacter hormaechei