Re: Inadequacy of PCR genotyping in advanced non-small cell lung cancer: EGFR L747_A755delinsSS Exon 19 deletion is not detected by the real-time PCR IdyllaTM EGFR mutation test but is detected by ctDNA NGS and responds to osimertinib

Eur J Cancer. 2022 Oct:174:315-317. doi: 10.1016/j.ejca.2022.06.039. Epub 2022 Aug 4.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Acrylamides
  • Aniline Compounds / therapeutic use
  • Carcinoma, Non-Small-Cell Lung* / drug therapy
  • Carcinoma, Non-Small-Cell Lung* / genetics
  • Circulating Tumor DNA* / genetics
  • ErbB Receptors / genetics
  • Exons
  • Genotype
  • Humans
  • Indoles
  • Lung Neoplasms* / drug therapy
  • Lung Neoplasms* / genetics
  • Mutation
  • Protein Kinase Inhibitors / therapeutic use
  • Pyrimidines
  • Real-Time Polymerase Chain Reaction

Substances

  • Acrylamides
  • Aniline Compounds
  • Circulating Tumor DNA
  • Indoles
  • Protein Kinase Inhibitors
  • Pyrimidines
  • osimertinib
  • EGFR protein, human
  • ErbB Receptors