NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors

Reports (MDPI). 2021 Dec;4(4):32. doi: 10.3390/reports4040032. Epub 2021 Oct 1.


"Tumor-educated platelets" have recently generated substantial interest for the diagnosis of cancer. We hypothesized that tumor educated platelets from patients with brain tumors will reflect altered metabolism compared to platelets from healthy volunteers. Here, in a pilot study, we have employed nuclear magnetic resonance (NMR) spectroscopy in platelets from brain tumor patients to demonstrate altered metabolism compared to the platelets obtained from healthy volunteers.

Keywords: NMR spectroscopy; biomarkers; brain tumor; metabolomics; platelets.