Immunostimulating properties and three-dimensional structure of two tripeptides from human and cow caseins

FEBS Lett. 1987 Jun 22;218(1):55-8. doi: 10.1016/0014-5793(87)81017-7.

Abstract

Some tripeptides obtained by enzymic digestion of caseins possess immunomodulating properties. In order to correlate activity and structure, X-ray analysis has been applied to two of them Leu-Leu-Tyr and Gly-Leu-Phe.

Publication types

  • Comparative Study

MeSH terms

  • Adjuvants, Immunologic / immunology*
  • Animals
  • Caseins / analysis
  • Caseins / immunology*
  • Caseins / pharmacology
  • Cattle
  • Humans
  • Immunity, Innate / drug effects
  • Klebsiella Infections / immunology
  • Macrophages / drug effects
  • Mice
  • Models, Molecular
  • Peptide Fragments / immunology*
  • Peptide Fragments / isolation & purification
  • Peptide Fragments / pharmacology
  • Phagocytosis / drug effects
  • Protein Conformation
  • X-Ray Diffraction

Substances

  • Adjuvants, Immunologic
  • Caseins
  • Peptide Fragments