Hepatic encephalopathy and strategies to prevent readmission from inadequate transitions of care

J Hosp Med. 2022 Aug;17 Suppl 1:S17-S23. doi: 10.1002/jhm.12896.


One of the most costly and frequent causes of hospital readmissions in the United States is hepatic encephalopathy in patients with underlying liver cirrhosis. In this narrative review, we cover current practices in inpatient management, transitions of care, and strategies to prevent hospital readmissions. Bundled approaches using a model such as the "Ideal Transitions of Care" appear to be more likely to prevent readmissions and assist patients as they transition to outpatient care. Numerous strategies have been evaluated to prevent readmissions in patients with hepatic encephalopathy, including technologic interventions, involvement of nonphysician team members, early follow-up strategies, and involvement of palliative care when appropriate.

Publication types

  • Review

MeSH terms

  • Ambulatory Care
  • Hepatic Encephalopathy* / therapy
  • Humans
  • Inpatients
  • Liver Cirrhosis / complications
  • Liver Cirrhosis / therapy
  • Patient Readmission
  • United States