Epigenetic regulation in the shoot apical meristem

Curr Opin Plant Biol. 2022 Oct;69:102267. doi: 10.1016/j.pbi.2022.102267. Epub 2022 Aug 16.

Abstract

Epigenetic mechanisms form the basis of cellular memory, developmental decisions, and the cellular immune system that defends against transposons and viruses. Organs develop from the shoot apical meristem (SAM) to shape the plant's areal phenotype, and stem cells in the SAM serve as a functional germline. While many details on the regulation of stem cell pool size, organ initiation, and patterning at the meristem periphery are known, we know surprisingly little about the molecular characteristics of SAM cells, including their epigenome and how it changes during development. Here, we summarize information on epigenetic regulation of selected genes necessary for stem cell maintenance. As recent evidence suggests that SAM stem cells might be a hotspot of transposon activation, we discuss this aspect of epigenetic control in the meristem and speculate on mechanisms that maintain the flexibility of SAM stem cells in response to developmental or environmental cues.

Keywords: AGAMOUS (AG); CLAVATA3 (CLV3); Chromatin; DNA methylation; Histone PTMs (H3K27me3, H3K4me3); L2 layer; LTR/Gypsy; Plant virus; SAM; Shoot apical meristem; Small RNAs (sRNAs); Stem cells; Transposon; WUSCHEL (WUS).

Publication types

  • Review

MeSH terms

  • Arabidopsis Proteins* / metabolism
  • Arabidopsis* / genetics
  • Epigenesis, Genetic
  • Gene Expression Regulation, Plant / genetics
  • Homeodomain Proteins / genetics
  • Homeodomain Proteins / metabolism
  • Meristem
  • Plant Shoots / metabolism

Substances

  • Arabidopsis Proteins
  • Homeodomain Proteins