Neurologic complications after cardiopulmonary bypass - A narrative review

Perfusion. 2023 Nov;38(8):1545-1559. doi: 10.1177/02676591221119312. Epub 2022 Aug 19.

Abstract

Neurologic complications, associated with cardiac surgery and cardiopulmonary bypass (CPB) in adults, are common and can be devastating in some cases. This comprehensive review will not only consider the broad categories of stroke and neurocognitive dysfunction, but it also summarises other neurological complications associated with CPB, and it provides an update about risks, prevention and treatment. Where appropriate, we consider the impact of off-pump techniques upon our understanding of the contribution of CPB to adverse outcomes.

Keywords: Cardiac surgery; postoperative cognitive dysfunction; postoperative delirium; postoperative neurocognitive disorders; postoperative neurological complications; postoperative stroke.

Publication types

  • Review

MeSH terms

  • Adult
  • Cardiac Surgical Procedures* / adverse effects
  • Cardiac Surgical Procedures* / methods
  • Cardiopulmonary Bypass / adverse effects
  • Cardiopulmonary Bypass / methods
  • Humans
  • Nervous System Diseases* / etiology
  • Postoperative Complications / etiology
  • Stroke* / etiology