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. 2023 Aug 1;57(7):731-736.
doi: 10.1097/MCG.0000000000001743.

Racial and Ethnic Disparities Among Patients Hospitalized for Acute Cholangitis in the United States

Melinda Wang  1 , Sharad I Wadhwani  2 , Giuseppe Cullaro  3 , Jennifer C Lai  3 , Jessica B Rubin  3
Affiliations

Racial and Ethnic Disparities Among Patients Hospitalized for Acute Cholangitis in the United States

Melinda Wang et al. J Clin Gastroenterol. .

Abstract

Goals: We sought to determine whether race/ethnicity is associated with hospitalization outcomes among patients admitted with acute cholangitis.

Background: Few studies have evaluated the association between race and outcomes in patients with acute cholangitis.

Study: We analyzed United States hospitalizations from 2009 to 2018 using the Nationwide Inpatient Sample (NIS). We included patients 18 years old or above admitted with an ICD9/10 diagnosis of cholangitis. Race/ethnicity was categorized as White, Black, Hispanic, or Other. We used multivariable regression to determine the association between race/ethnicity and in-hospital outcomes of interest, including endoscopic retrograde cholangiopancreatography (ERCP), early ERCP (<48 h from admission), length of stay (LOS), and in-hospital mortality.

Results: Of 116,889 hospitalizations for acute cholangitis, 70% identified as White, 10% identified as Black, 11% identified as Hispanic, and 9% identified as Other. The proportion of non-White patients increased over time. On multivariate analysis controlling for clinical and sociodemographic variables, compared with White patients, Black patients had higher in-hospital mortality (adjusted odds ratio: 1.4, 95% confidence interval: 1.2-1.6, P <0.001). Black patients were also less likely to undergo ERCP, more likely to undergo delayed ERCP, and had longer LOS ( P <0.001 for all).

Conclusions: In this contemporary cohort of hospitalized patients with cholangitis, Black race was independently associated with fewer and delayed ERCP procedures, longer LOS, and higher mortality rates. Future studies with more granular social determinants of health data should further explore the underlying reasons for these disparities to develop interventions aimed at reducing racial disparities in outcomes among patients with acute cholangitis.

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Conflict of interest statement

Potential competing interests: The authors have no conflicts of interest to disclose.

Figures

Figure 1.
Figure 1.
Proportion of acute cholangitis hospitalizations among non-White patients by year, 2007–2018.
Figure 2.
Figure 2.
Adjusted Risk of Hospital Outcomes in Patients with Acute Cholangitis by Race / Ethnicity including ERCP, early ERCP, hospital length of stay (LOS), and in-hospital mortality.
See this image and copyright information in PMC

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