doi: 10.1128/jb.124.3.1148-1152.1975.
Phospholipase D activity of gram-negative bacteria
- PMID: 360
- PMCID: PMC236020
- DOI: 10.1128/jb.124.3.1148-1152.1975
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Phospholipase D activity of gram-negative bacteria
J Bacteriol.
1975 Dec.
Abstract
A phospholipase hydrolyzing cardiolipin to phosphatidic acid and phosphatidyl glycerol was characterized in gram-negative bacteria but was absent in preparations of gram-positive bacteria, Saccharomyces cerevisiae, and rat liver mitochondria. In cell-free extracts of Escherichia coli, Salmonella typhimurium, Proteus vulgaris, and Pseudomonase aeruginosa, this cardiolipin-hydrolyzing enzyme had similar pH and Mg2+ requirements and displayed a specificity which excluded phosphatidyl glycerol and phosphatidyl ethanolamine as substrates.
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