Nipple Adenoma: A Benign Disease With a Suspicious Presentation

Am Surg. 2023 Dec;89(12):6243-6245. doi: 10.1177/00031348221117026. Epub 2022 Aug 25.

Abstract

Nipple adenoma is a rare proliferative lesion that originates from the lactiferous ducts of the nipple. Though it is benign, the typical presentation includes suspicious symptoms-a firm nodule, crusting erosion, and/or discharge from the nipple. These findings can raise concern for malignancy and in particular, Paget's disease. We report two cases of this uncommon entity, highlighting the variable clinical presentation and keys to the diagnostic evaluation and management.

Keywords: nipple adenoma; paget’s disease.

MeSH terms

  • Breast Neoplasms* / diagnosis
  • Breast Neoplasms* / pathology
  • Breast Neoplasms* / surgery
  • Diagnosis, Differential
  • Female
  • Humans
  • Nipples / pathology
  • Paget's Disease, Mammary* / diagnosis
  • Paget's Disease, Mammary* / pathology
  • Paget's Disease, Mammary* / surgery
  • Papilloma* / diagnosis
  • Papilloma* / pathology

Supplementary concepts

  • Erosive Adenomatosis of the Nipple