Biopharmaceutical R&D outsourcing: Short-term gain for long-term pain?

Drug Discov Today. 2022 Nov;27(11):103333. doi: 10.1016/j.drudis.2022.08.001. Epub 2022 Aug 22.

Abstract

Research and development (R&D) outsourcing offers some obvious productivity benefits (e.g., access to new technology, variabilised costs, risk sharing, etc.). However, recent work in economics points to a productivity headwind at the level of the innovation ecosystem. The market for technologies with economies of scope and knowledge spillovers (those with the biggest impact on industry economics and social welfare) has structural features that allow customers to capture a disproportionate share of economic value and transfer a disproportionate share of economic risk to technology providers, even though the providers aim to maximise profit. This reduces the incentives to invest in new ventures that specialise in the most promising early-stage projects. Therefore, near-term gains from R&D outsourcing can be offset by slower innovation in the long run.

Keywords: Biotechnology; Development; Externalities; Outsourcing; Pharmaceuticals; Research.

Publication types

  • Review