Panic disorder precipitated by exposure to organic solvents in the work place

Am J Psychiatry. 1987 Aug;144(8):1056-8. doi: 10.1176/ajp.144.8.1056.


The authors describe three cases of idiosyncratic response to occupational solvent exposure, with symptoms characteristic of panic disorder (DSM-III). The specific treatment and prognostic implications of this panic-like reaction to solvents are discussed. Sodium lactate infusion is proposed as an objective test to aid in the diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anxiety Disorders / chemically induced*
  • Anxiety Disorders / diagnosis
  • Fear*
  • Female
  • Humans
  • Lactates
  • Lactic Acid
  • Male
  • Occupational Diseases / chemically induced*
  • Occupational Diseases / diagnosis
  • Panic*
  • Solvents / adverse effects*


  • Lactates
  • Solvents
  • Lactic Acid