Improved erythema and decreased blister formation in dominant dystrophic epidermolysis bullosa following treatment with pulsed dye laser

Pediatr Dermatol. 2022 Nov;39(6):1005-1006. doi: 10.1111/pde.15126. Epub 2022 Sep 5.

Abstract

Dominant dystrophic epidermolysis bullosa (DDEB), an inherited disorder due to type VII collagen mutations, is characterized by blisters and erosions that heal with scarring, atrophy, and milia. There is no established role for laser in the management of patients with DDEB. Pulsed dye laser (PDL) is most often used to target vascular skin lesions. We describe a patient with DDEB with marked improvement in erythema as well as fewer and less symptomatic episodes of blistering following treatment with PDL.

Keywords: collagen type VII; dystrophic; epidermolysis bullosa; lasers; pulsed dye; wound healing.

Publication types

  • Case Reports

MeSH terms

  • Blister / etiology
  • Blister / pathology
  • Collagen Type VII / genetics
  • Epidermolysis Bullosa Dystrophica* / complications
  • Epidermolysis Bullosa Dystrophica* / genetics
  • Epidermolysis Bullosa Dystrophica* / radiotherapy
  • Erythema / etiology
  • Erythema / pathology
  • Humans
  • Lasers, Dye* / therapeutic use
  • Skin / pathology
  • Soft Tissue Injuries*

Substances

  • Collagen Type VII