Rare Concurrence of Alopecia Areata in the Setting of the Lipedematous Scalp

Am J Dermatopathol. 2022 Nov 1;44(11):831-833. doi: 10.1097/DAD.0000000000002261. Epub 2022 Sep 1.

Abstract

The lipedematous scalp (LS) is characterized by a thickened scalp because of the increased thickness of the subcutaneous fat layer. When the soft and boggy scalp is associated with shortened hairs and hair loss, it is referred to as lipedematous alopecia (LA). We report a case of alopecia areata with LS, which may be misdiagnosed as LA. However, the histopathologic features showed a thickened subcutaneous fat layer and hair bulb inflammation. Hair regrowth was appreciable after treatment with topical steroids, minoxidil, oral compound glycyrrhizin, and vitamin D. This case report aims to show that LS and alopecia areata may coexist, and histopathologic examination is necessary for precise diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Alopecia / pathology
  • Alopecia Areata* / complications
  • Alopecia Areata* / drug therapy
  • Alopecia Areata* / pathology
  • Glycyrrhizic Acid
  • Humans
  • Lipedema*
  • Minoxidil
  • Scalp / pathology
  • Vitamin D

Substances

  • Vitamin D
  • Minoxidil
  • Glycyrrhizic Acid

Supplementary concepts

  • Diffuse alopecia