Editorial Comment: Iron-sensitive MR imaging of the primary motor cortex to differentiate hereditary spastic paraplegia from other motor neuron diseases

Eur Radiol. 2022 Dec;32(12):8055-8057. doi: 10.1007/s00330-022-09093-8. Epub 2022 Sep 8.

Abstract

• Conventional and advanced MR techniques may aid in the diagnosis of motor neuron disease.• Iron-sensitive MR imaging of the primary motor cortex may reveal changes to help differentiate hereditary spastic paraplegia (HSP) from UMM predominant amyotrophic lateral sclerosis (UMN-ALS) and primary lateral sclerosis (PLS).• Additional research in this area is necessary.

Keywords: Amyotrophic lateral sclerosis; Hereditary spastic paraplegia; Magnetic resonance imaging; Primary lateral sclerosis; Primary motor cortex.

Publication types

  • Editorial
  • Comment

MeSH terms

  • Amyotrophic Lateral Sclerosis* / diagnosis
  • Humans
  • Iron
  • Magnetic Resonance Imaging / methods
  • Motor Cortex* / diagnostic imaging
  • Motor Neuron Disease* / diagnostic imaging
  • Spastic Paraplegia, Hereditary* / diagnostic imaging

Substances

  • Iron