Outcome of subsequent pregnancies post uterine rupture in previous delivery: A case series, a review, and recommendations for appropriate management

Int J Gynaecol Obstet. 2023 Apr;161(1):204-217. doi: 10.1002/ijgo.14445. Epub 2022 Oct 2.

Abstract

Objectives: To provide clinicians with concrete solutions on the best management of and counseling for patients in a subsequent pregnancy following uterine rupture.

Methods: A retrospective analysis of patients treated between 2005 and 2020 at Sheba Medical Center was conducted. All patients who had undergone a complete uterine rupture and subsequently had a full-term pregnancy were included. A literature review was conducted using Pubmed database and including previously published literature reviews.

Results: Fifteen patients with subsequent pregnancies following uterine rupture were included in our cohort. Mean interval between rupture and subsequent pregnancy was 3.8 years (range 2.2-6.9 years). One patient had repeat uterine rupture of less than 2 cm at 36+5 weeksof pregnancy. A total of 17 studies were selected in this literature review, including a total of 774 pregnancies in 635 patients. The risk of repeated uterine rupture was 8.0% (62/774), ranging from 0% to 37.5%. Overall, the risk of maternal death was of 0.6% (4/635), with only four cases reported in three studies.

Conclusion: The risk of recurrence after uterine rupture is significant but should not prevent patients from conceiving.

Keywords: repeat; subsequent pregnancy; uterine rupture; uterine ruptureCesarean scar.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Pregnancy
  • Pregnancy Outcome
  • Retrospective Studies
  • Uterine Rupture* / epidemiology
  • Uterine Rupture* / etiology
  • Uterus