Experimental genital trichomoniasis in the squirrel monkey (Saimiri sciureus)

Genitourin Med. 1987 Jun;63(3):188-91. doi: 10.1136/sti.63.3.188.

Abstract

The squirrel monkey (Saimiri sciureus) has been proposed as a model for urogenital trichomoniasis in man, but has not been accepted as such because of the purported presence of naturally occurring vaginal trichomonads in this animal. The study published here shows that these are easily eradicated organisms of intestinal origin, which eliminates the potential confusion created by them. In addition, our experiments have shown that the hormonal status of primates seems to be a determinant in successfully establishing experimental trichomoniasis. This experimental infection recapitulates the clinical observations sufficiently to warrant the use of this model for studies of vaginal trichomoniasis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cebidae*
  • Cervix Uteri / pathology
  • Disease Models, Animal*
  • Female
  • Saimiri*
  • Trichomonas Vaginitis* / pathology