Biomedical applications of iron sulfide-based nanozymes

Yunyi Shan; Wenjie Lu; Juqun Xi; Yayun Qian

doi:10.3389/fchem.2022.1000709

Biomedical applications of iron sulfide-based nanozymes

Front Chem. 2022 Aug 29:10:1000709. doi: 10.3389/fchem.2022.1000709. eCollection 2022.

Authors

Yunyi Shan¹, Wenjie Lu¹, Juqun Xi^{1

2}, Yayun Qian^{1

2}

Affiliations

¹ Department of Pharmacology, School of Medicine, Institute of Translational Medicine, Yangzhou University, Yangzhou, China.
² Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Yangzhou, China.

Abstract

Nanozymes have attracted great interest owing to their marvelous advantages, such as high stability, facile preparation, and high tunability. In particular, iron sulfide-based nanozymes (termed as ISNs), as one of the most researched nanomaterials with versatile enzyme-mimicking properties, have proved their potential in biomedical applications. In this review, we briefly summarize the classification, catalytic mechanisms of ISNs and then principally introduce ISNs' biomedical applications in biosensors, tumor therapy, antibacterial therapy, and others, demonstrating that ISNs have promising potential for alleviating human health.

Keywords: biomedical applications; catalytic mechanism; classification; iron sulfides; nanozymes.

Publication types

Review