A meta-analysis of CBT efficacy for depression comparing adults and older adults

J Affect Disord. 2022 Dec 15:319:189-201. doi: 10.1016/j.jad.2022.09.020. Epub 2022 Sep 13.

Abstract

Introduction: This meta-analysis investigates CBT treatment efficacy fordepression, and compares outcomes between adults (young and middle aged) and older adults (OA).

Methodology: Effect sizes (Hedges' g) were obtained from 37 peer-reviewed RCTs, 25 adult papers (participant n = 2948) and 12 OA papers (participant n = 551), and analysed with the random effects model.

Results: No significant difference between age groups is reported in terms of CBT efficacy for depression compared to other treatments (Qbetween (1) = 0.06, p = .89), with the overall effect favouring CBT over any other treatments (g = 0.48, 95 % CI = 0.29-0.68). The same pattern of results was found when restricting studies to those which used active control conditions (Qbetween (1) = 0.03, p = .86) or passive control conditions (Q (1) = 2.45, p = .12).

Discussion: No significant differences in efficacy for CBT treatment for depression are found when comparing adults and OA. CBT is as efficacious with OA as with adults.

Keywords: CBT; Cognitive behavioral therapy; Depression; Major depressive disorder; Meta-analysis; Middle aged adults; Older adults; Older people; Young adults.

Publication types

  • Meta-Analysis

MeSH terms

  • Aged
  • Cognitive Behavioral Therapy* / methods
  • Depression / therapy
  • Humans
  • Middle Aged
  • Treatment Outcome