Critical Care of the Lung Transplant Patient

Clin Chest Med. 2022 Sep;43(3):457-470. doi: 10.1016/j.ccm.2022.04.007.


Lung transplantation is a therapeutic option for end-stage lung disease that improves survival and quality of life. Prelung transplant admission to the intensive care unit (ICU) for bridge to transplant with mechanical ventilation and extracorporeal membrane oxygenation (ECMO) is common. Primary graft dysfunction is an important immediate complication of lung transplantation with short- and long-term morbidity and mortality. Later transplant-related causes of respiratory failure necessitating ICU admission include acute cellular rejection, atypical infections, and chronic lung allograft dysfunction. Lung transplantation for COVID-19-related ARDS is increasingly common..

Keywords: Long-term complications of lung transplant; Lung transplant Candidacy; The immediate postlung transplant Patient in the ICU; The prelung transplant Patient in the ICU; Transplant and COVID-19.

Publication types

  • Review

MeSH terms

  • COVID-19*
  • Critical Care
  • Humans
  • Lung Transplantation* / adverse effects
  • Quality of Life
  • Treatment Outcome