Comprehensive investigation of the content and the origin of matrine-type alkaloids in Chinese honeys

Zhiying Wang; Tiehong Zu; Xuezhe Huang; Xiaolin Jiang; Guangqun Jia; Jinzhong Xu; Zongyan Cui; Fengmei Zhu; Jinjie Zhang; Jun Li; Yanzhong Cao

doi:10.1016/j.foodchem.2022.134254

Comprehensive investigation of the content and the origin of matrine-type alkaloids in Chinese honeys

Food Chem. 2023 Feb 15:402:134254. doi: 10.1016/j.foodchem.2022.134254. Epub 2022 Sep 14.

Authors

Zhiying Wang¹, Tiehong Zu², Xuezhe Huang², Xiaolin Jiang², Guangqun Jia², Jinzhong Xu³, Zongyan Cui⁴, Fengmei Zhu⁵, Jinjie Zhang¹, Jun Li⁶, Yanzhong Cao²

Affiliations

¹ Technology Center of Qinhuangdao Customs, Qinhuangdao 066004, China; College of Food Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066004, China.
² Technology Center of Qinhuangdao Customs, Qinhuangdao 066004, China.
³ Nanjing Zhongpu Biotechnology Co. Ltd, Nanjing 210032, Jiangsu, China.
⁴ Technology Center of Qinhuangdao Customs, Qinhuangdao 066004, China; College of Food Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066004, China. Electronic address: ciqqhd@126.com.
⁵ College of Food Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066004, China. Electronic address: zhufengmei0714@163.com.
⁶ College of Food Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066004, China.

PMID: 36126585
DOI: 10.1016/j.foodchem.2022.134254

Abstract

A HPLC-MS/MS method for simultaneous determination of four matrine-type alkaloids (matrine, oxymatrine, sophocarpine and sophoridine) in honey was established and was applied to 567 Chinese honey samples. The overall detection rate was 61.0 % and all eight Sophora viciifolia Hance honey samples were detected with the average content of 1183.3 μg/kg. Among 383 Acacia honey samples, matrine-type alkaloids have the highest detection rates in Gansu (98.8 %) and Shaanxi (86.5 %) provinces, which were significantly correlated with the distribution of S. viciifolia Hance. Moreover, matrine-type alkaloids in fruits and flowers of S. viciifolia Hance were as high as 7.06 g/kg and 2.65 g/kg respectively. The melissopalynological analysis showed that the concentration of oxymatrine was positively correlated with the pollen frequency of S. viciifolia Hance (R² = 0.737) in representative Acacia honey samples. It can be concluded that the matrine-type alkaloids in Chinese honeys come from the nectariferous plants S. viciifolia Hance.

Keywords: Chinese Honey; HPLC-MS/MS; Matrine; Origin; Oxymatrine; Sophora viciifolia Hance.

MeSH terms

Alkaloids* / analysis
China
Honey* / analysis
Matrines
Tandem Mass Spectrometry

Substances

Alkaloids
Matrines