Fluorescence perfusion assessment of vascular ligation during ileal pouch-anal anastomosis

Tech Coloproctol. 2023 Apr;27(4):281-290. doi: 10.1007/s10151-022-02666-1. Epub 2022 Sep 21.

Abstract

Background: Intraoperative fluorescence angiography (FA) is of potential added value during ileal pouch-anal anastomosis (IPAA), especially after vascular ligation as part of lengthening measures. In this study, time to fluorescent enhancement during FA was evaluated in patients with or without vascular ligation during IPAA.

Methods: This is a retrospective cohort study of all consecutive patients that underwent FA-guided IPAA between August 2018 and December 2019 in our tertiary referral centre. Vascular ligation was defined as disruption of the ileocolic arcade or ligation of interconnecting terminal ileal branches. FA was performed before and after ileoanal anastomotic reconstruction. During FA, time to fluorescent enhancement was recorded at different sites of the pouch.

Results: Thirty-eight patients [55.3% male, median age 45 years (IQR 24-51 years)] were included, of whom the majority (89.5%) underwent a modified-2-stage restorative proctocolectomy. Vascular ligation was performed in 15 patients (39.5%), and concerned central ligation of the ileocolic arcade in 3 cases, interconnecting branches in 10, and a combination in 2. For the entire cohort, time between indocyanine green (ICG) injection and first fluorescent signal in the pouch was 20 s (IQR 15-31 s) before and 25 s (IQR 20-36 s) after anal anastomotic reconstruction. Time from ICG injection to the first fluorescent signal at the inlet, anvil and blind loop of the pouch were non-significantly prolonged in patients that received vascular ligation.

Conclusions: Results from this study indicate that time to fluorescence enhancement during FA might be prolonged due to arterial rerouting through the arcade or venous outflow obstruction in case of vascular ligation.

Keywords: Anastomotic leakage; Fluorescence angiography; Ileal pouch-anal anastomosis (IPAA); Indocyanine green (ICG); Vascular ligation.

MeSH terms

  • Anastomosis, Surgical
  • Colitis, Ulcerative* / surgery
  • Colonic Pouches*
  • Female
  • Humans
  • Ileum / surgery
  • Male
  • Middle Aged
  • Perfusion
  • Postoperative Complications / surgery
  • Proctocolectomy, Restorative* / methods
  • Retrospective Studies