Combination GnRH antagonists for endometriosis: Balancing efficacy with side effects

Cell Rep Med. 2022 Sep 20;3(9):100748. doi: 10.1016/j.xcrm.2022.100748.

Abstract

Endometriosis is a chronic pain condition affecting 1 in 10 women. There is an unmet need for better medical treatments for endometriosis. We spotlight trials of a single preparation combined HRT-GnRH antagonist (Relugolix) by Giudice et al.,1 for endometriosis-associated pain.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Drug-Related Side Effects and Adverse Reactions* / drug therapy
  • Endometriosis* / drug therapy
  • Female
  • Gonadotropin-Releasing Hormone / therapeutic use
  • Hormone Antagonists / adverse effects
  • Humans
  • Pain / chemically induced

Substances

  • Hormone Antagonists
  • Gonadotropin-Releasing Hormone