Exportin-inspired artificial cell nuclear-exporting nanosystems

Nanoscale Adv. 2022 May 12;4(12):2637-2641. doi: 10.1039/d2na00050d. eCollection 2022 Jun 14.

Abstract

Inspired by the structural and chemical features of naturally occurring importin/exportin that allows them to pass through the nuclear pore complexes, we successfully developed an artificial nuclear-exporting nanosystem capable of eliminating compounds accumulated abnormally in the nucleus.