Hypertrophic Osteopathy Associated with a Prostatic Adenocarcinoma in a Castrated Dog

Vet Sci. 2022 Aug 30;9(9):466. doi: 10.3390/vetsci9090466.


A 6-year-old mixed-breed male Papillon dog, castrated at the age of 7 months, presented for work-up of a difficulty walking associated with constipation and urinary incontinence. Ultrasonography and radiography were consistent with a tumor of the prostate and lymph node metastases. An irregular osteoproliferation of the ventral edges of L5-L6-L7 suggested tumor invasion. Periosteal proliferative lesions of the pelvis, the femur, the humerus, the tibia and the calcaneus were consistent with hypertrophic osteopathy. Necropsy and histological examination confirmed the diagnosis of prostatic adenocarcinoma with lymph node, pulmonary, liver and bone metastases, associated with hypertrophic osteopathy.

Keywords: cancer; dog; hypertrophic osteopathy; paraneoplastic syndrome; prostate; prostatic adenocarcinoma.

Publication types

  • Case Reports

Grant support

This research received no external funding.