In this paper, the follow-up results of a long-term study of industrial workers are presented. In themselves, these results may be of interest. It is, however, in the context of all the known facts, in its synthesis with other studies that this human experience in pesticide manufacturing assumes its proper significance. Therefore, related animal and other studies are briefly mentioned before the results of our clinical--epidemiological human study. Thus, the latter can be placed in context, and conclusions can be based on all the established facts rather than on the opinions on isolated aspects.