Sixteen-Year Follow-Up in a Cavernous Sinus Hemangiopericytoma: Improved Outcomes over Radiotherapy Advances

Brain Sci. 2022 Sep 8;12(9):1209. doi: 10.3390/brainsci12091209.

Abstract

Intracranial hemangiopericytomas are rare tumors, accounting for 1% of all central nervous system malignancies. This tumor is considered at high risk of local and also distant metastases. Surgical excision is the gold standard for treatment, but it is seldom curative by itself. Adjuvant radiotherapy is often recommended. We report an overview and update of the available literature on one such rare but aggressive mesenchymal tumor, using the case of a 46-year-old woman affected by hemangiopericytoma of the cavernous sinus surgically removed and treated with adjuvant radiotherapy at our institution. After seven years, the patient underwent a local recurrence and was treated with exeresis and Gamma Knife radiotherapy. Sixteen years after the initial diagnosis, she is still well with stable disease.

Keywords: Gamma Knife; intracranial hemangiopericytomas; radiotherapy; stereotactic radiosurgery; surgery.

Publication types

  • Case Reports

Grants and funding

This research received no external funding. This study was partially supported by the Italian Ministry of Health—Ricerca Corrente.