Fluorescence-Guided Surgery and Novel Innovative Technologies for Improved Visualization in Pediatric Urology

Int J Environ Res Public Health. 2022 Sep 6;19(18):11194. doi: 10.3390/ijerph191811194.

Abstract

Fluorescence-guided surgery (FGS), three-dimensional (3D) imaging technologies, and other innovative devices are rapidly revolutionizing the field of urology, providing surgeons with powerful tools for a more complete understanding of patient-specific anatomy. Today, several new intraoperative imaging technologies and cutting-edge devices are available in adult urology to assist surgeons in delivering personalized interventions. Their applications are also gradually growing in general pediatric surgery, where the detailed visualization of normal and pathological structures has the potential to significantly minimize perioperative complications and improve surgical outcomes. In the field of pediatric urology, FGS, 3D reconstructions and printing technologies, augmented reality (AR) devices, contrast-enhanced ultrasound (CEUS), and intraoperative magnetic resonance imaging (iMRI) have been increasingly adopted for a more realistic understanding of the normal and abnormal anatomy, providing a valuable insight to deliver customized treatments in real time. This narrative review aims to illustrate the main applications of these new technologies and imaging devices in the clinical setting of pediatric urology by selecting, with a strict methodology, the most promising articles published in the international scientific literature on this topic. The purpose is to favor early adoption and stimulate more research on this topic for the benefit of children.

Keywords: 3D imaging; 3D printing; augmented reality; children; fluorescence-guided surgery; pediatric urology.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Augmented Reality*
  • Child
  • Fluorescence
  • Humans
  • Imaging, Three-Dimensional
  • Surgery, Computer-Assisted*
  • Urology*

Grants and funding

This work was supported by the “Associazione per il Bambino Nefropatico ABN Onlus”, 20122, Via Commenda 16, Milan, Italy, and by the “Centro di riferimento per le malformazioni congenite del rene e delle vie urinarie: prevenzione e cura del danno renale dal feto al bambino Sergio Bonelli”. This study was funded by the Italian Ministry of Health—Fondazione IRCCS Cà Granda Ospedale Maggiore Policinico, Milano, Italy.