Antibacterial Effects of Phytocannabinoids

Life (Basel). 2022 Sep 7;12(9):1394. doi: 10.3390/life12091394.


Antibiotics are used as the first line of treatment for bacterial infections. However, antibiotic resistance poses a significant threat to the future of antibiotics, resulting in increased medical costs, hospital stays, and mortality. New resistance mechanisms are emerging and spreading globally, impeding the success of antibiotics in treating common infectious diseases. Recently, phytocannabinoids have been shown to possess antimicrobial activity on both Gram-negative and Gram-positive bacteria. The therapeutic use of phytocannabinoids presents a unique mechanism of action to overcome existing antibiotic resistance. Future research must be carried out on phytocannabinoids as potential therapeutic agents used as novel treatments against resistant strains of microbes.

Keywords: antibiotics; cannabinoids; infection; inflammation.

Publication types

  • Review

Grants and funding

This research received no external funding.