Pharmacologic Treatment of Sleep Disorders in Pregnancy

Laura P McLafferty; Meredith Spada; Priya Gopalan

doi:10.1016/j.jsmc.2022.06.009

Pharmacologic Treatment of Sleep Disorders in Pregnancy

Sleep Med Clin. 2022 Sep;17(3):445-452. doi: 10.1016/j.jsmc.2022.06.009.

Authors

Laura P McLafferty¹, Meredith Spada², Priya Gopalan²

Affiliations

¹ Department of Psychiatry and Human Behavior, Thomas Jefferson University, Thompson Building, Suite 1652, 1020 Sansom Street, Philadelphia, PA 19107, USA. Electronic address: laura.mclafferty@jefferson.edu.
² Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

PMID: 36150806
DOI: 10.1016/j.jsmc.2022.06.009

Abstract

Pregnancy is a unique physiologic state whose characteristics often predispose women to new-onset sleep disturbances or exacerbations of preexisting sleep disorders. Pregnancy-related factors that can disrupt sleep include heartburn, nocturnal oxytocin secretion, nocturia, and fetal movement. Sleep disorders in pregnancy include insomnia (primary and secondary), restless legs syndrome, and narcolepsy.

Keywords: Insomnia; Narcolepsy; Pregnancy; Restless legs syndrome; Sleep aids; Sleep disorders.

Publication types

Review

MeSH terms

Female
Humans
Narcolepsy* / drug therapy
Oxytocin / therapeutic use
Pregnancy
Restless Legs Syndrome* / therapy
Sleep Initiation and Maintenance Disorders* / complications
Sleep Wake Disorders* / complications
Sleep Wake Disorders* / drug therapy

Substances

Oxytocin