Relationships Between Atrial Flutter and Fibrillation: The Border Zone

Card Electrophysiol Clin. 2022 Sep;14(3):421-434. doi: 10.1016/j.ccep.2022.06.006. Epub 2022 Aug 25.


Atrial flutter and fibrillation have been inextricably linked in the study of electrophysiology. With astute clinical observation, advanced diagnostic equipment in the Electrophysiology Laboratory, and thoughtful study of animal models, the mechanism and inter-relationship between the 2 conditions have been elucidated and will be reviewed in this article. Though diagnosis and management of these conditions have many similarities, the mechanisms by which they develop and persist are quite unique.

Keywords: Atrial fibrillation; Atrial flutter; Line of block; Radiofrequency ablation.

Publication types

  • Review

MeSH terms

  • Animals
  • Atrial Fibrillation* / surgery
  • Atrial Flutter*
  • Catheter Ablation*
  • Humans