Anti-bacterial effects of functional cosmetics containing silver ions (Ag+ ) on problematic toenails in Republic of Korea

J Cosmet Dermatol. 2022 Nov;21(11):6005-6009. doi: 10.1111/jocd.14451. Epub 2022 Sep 25.

Abstract

Background: Problematic toenails caused by various diseases that are infected by various bacteria are discolored or deformed if left unattended for a long time are gradually increasing in modern society. Accordingly, the present study examines the anti-bacterial effects of LCN products, focused on Pseudomonas aeruginosa and Trichophyton rubrum, which can appear in problematic toenail symptoms. After the treatment, a significant anti-bacterial effect occurring on problematic toenails when a product containing silver ion (Ag+ ) will be analyzed.

Methods: The anti-bacterial activity of LCN functional gel products in anti-fungal and/or anti-bacterial potency was confirmed by the paper disk method against two strains (Pseudomonas aeruginosa and Trichophyton rubum).

Results: From July 2019 to October 2019, 30 men and women in their 20s and 50s who needed to manage problematic toenails in Wonju city, Gangwon-do, Republic of Korea, were asked to use LCN products once every two weeks. After 4 months, changes in the managed toenails were observed. Both products showed very good anti-microbial activity against, Trichophyton rubum but a very weak one against Pseudomonas aeruginosa.

Conclusion: As a result of this study, although there was a difference between individuals, the feet treated with LCN products showed effective anti-bacterial activity against topical anti-bacterial effects.

Keywords: anti-bacterial; functional cosmetics; nail; onychomycosis; problematic toenails.

MeSH terms

  • Bacteria
  • Cosmetics* / pharmacology
  • Female
  • Foot Dermatoses* / microbiology
  • Humans
  • Male
  • Nails / microbiology
  • Onychomycosis* / microbiology
  • Republic of Korea
  • Silver / pharmacology

Substances

  • Silver
  • Cosmetics