Fatty filum terminale and low-lying conus medullaris in Gollop-Wolfgang complex: a case report and review of literature

Childs Nerv Syst. 2023 Feb;39(2):517-526. doi: 10.1007/s00381-022-05679-1. Epub 2022 Sep 26.

Abstract

Background/importance: Gollop-Wolfgang complex is a rare skeletal dysplasia with only 200 cases reported in the literature. This disorder is usually associated with several extraosseous anomalies. This report describes the first case of a fatty filum terminale and a low-lying conus medullaris in a patient with this complex. A review of the current literature of the Gollop-Wolfgang complex accompanies this case, highlighting the documented extraosseous anomalies seen in this complex.

Clinical presentation: We report a case of an 18-month-old patient with Gollop-Wolfgang complex who underwent cord untethering with release of the filum terminale after extensive workup showed the presence of a dyssynergic bladder and radiological evaluation revealed a fatty filum terminale and low-lying conus medullaris.

Conclusion: Gollop-Wolfgang complex is a skeletal dysplasia usually associated with several extra skeletal anomalies. Our report describes the first case of a fatty filum terminale and low-lying conus medullaris in this complex, as well as provides an overview of the documented anomalies seen in this disorder. A multidisciplinary approach is recommended when treating these infants in order to ensure that occult manifestations of the complex are not missed.

Keywords: Fatty filum terminale; Gollop-Wolfgang complex; Low-lying conus medullaris.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Abnormalities, Multiple* / diagnostic imaging
  • Bladder Exstrophy / diagnostic imaging
  • Cauda Equina* / diagnostic imaging
  • Female
  • Femur* / abnormalities
  • Femur* / diagnostic imaging
  • Hand Deformities, Congenital* / diagnostic imaging
  • Humans
  • Infant
  • Neurosurgical Procedures
  • Radiography
  • Spinal Cord* / diagnostic imaging
  • Spinal Cord* / surgery
  • Tibia* / abnormalities
  • Tibia* / diagnostic imaging

Supplementary concepts

  • Femur bifid with monodactylous ectrodactyly