Waardenburg syndrome-associated neurotrophic keratopathy in a child treated with neurotization surgery

Anania G Woldetensaye; Christopher Michael Runyan; Jagger C Koerner

doi:10.1016/j.jaapos.2022.08.262

Waardenburg syndrome-associated neurotrophic keratopathy in a child treated with neurotization surgery

J AAPOS. 2022 Dec;26(6):338-340. doi: 10.1016/j.jaapos.2022.08.262. Epub 2022 Sep 22.

Authors

Anania G Woldetensaye¹, Christopher Michael Runyan², Jagger C Koerner³

Affiliations

¹ Department of Ophthalmology, Wake Forest University School of Medicine, Winston Salem, North Carolina. Electronic address: ananiawold@gmail.com.
² Department of Plastic Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
³ Department of Ophthalmology, Wake Forest University School of Medicine, Winston Salem, North Carolina.

PMID: 36156299
DOI: 10.1016/j.jaapos.2022.08.262

Abstract

Waardenburg syndrome (WS) is a congenital developmental disorder characterized by congenital sensorineural hearing loss and pigmentary deficiencies in the iris, hair, and skin. Ocular associations of WS include choroidal and iris hypopigmentation and foveal hypoplasia. Possible associations include cataracts and retinal vein occlusion. We report the first case of neurotrophic cornea and relate our experience with neurotization surgery.

Publication types

Case Reports

MeSH terms

Child
Corneal Dystrophies, Hereditary*
Humans
Hypopigmentation*
Iris / surgery
Iris Diseases*
Nerve Transfer*
Waardenburg Syndrome* / complications
Waardenburg Syndrome* / diagnosis