Disseminated Intravascular Coagulation with Enhanced Fibrinolysis Caused by Heart Metastasis of Bladder Urothelial Carcinoma

Clara Helal; Tiphaine Lambert; Bérangère S Joly; Clément Dumont; Hélène Gauthier; Stéphane Culine

doi:10.1159/000523822

Disseminated Intravascular Coagulation with Enhanced Fibrinolysis Caused by Heart Metastasis of Bladder Urothelial Carcinoma

Case Rep Oncol. 2022 Aug 30;15(2):745-749. doi: 10.1159/000523822. eCollection 2022 May-Aug.

Authors

Clara Helal¹, Tiphaine Lambert¹, Bérangère S Joly², Clément Dumont¹, Hélène Gauthier¹, Stéphane Culine¹

Affiliations

¹ Department of Medical Oncology, Saint-Louis Hospital, AP-HP.Nord - Université de Paris, Paris, France.
² Department of Biological Hematology, Lariboisière Hospital, AP-HP.Nord - Université de Paris, Paris, France.

Abstract

Heart metastases from urothelial carcinoma of the bladder have rarely been reported in the literature. We present a case complicated by symptomatic disseminated intravascular coagulation in a 67-year-old woman. A rapid and sustained recovery from hemostatic troubles was obtained following fibrinogen supplementation combined with second-line paclitaxel chemotherapy.

Keywords: Bladder cancer; Disseminated intravascular coagulation; Heart metastasis; Urothelial carcinoma.

Publication types

Case Reports