Hexagonal boron nitride nanosheets based magnetic solid phase extraction for the extraction of phenoxy carboxylic acid herbicides from water samples followed by high-performance liquid chromatography-tandem mass spectrometry

Abstract

High-efficiency caption of pesticide residue is of vital significance for environmental safety monitoring. Herein, a hexagonal boron nitride nanosheets-based magnetic composite (Fe₃O₄@h-BNNSs) was synthesized and applied for the magnetic solid phase extraction (MSPE) of five phenoxy carboxylic acid (PCA) herbicides from water samples. Based on the π-π interaction, hydrogen bond and halogen bond, the Fe₃O₄@h-BNNSs composite showed excellent adsorption ability towards PCA herbicides. Several main variables that influenced the extraction efficiencies of PCA herbicides were investigated and optimized via single-factor experiment. Combining this Fe₃O₄@h-BNNSs composite-based MSPE with high-performance liquid chromatography-tandem mass spectrometry, a novel sensitive method for the analysis of PCA herbicides was developed. Under the most favorable conditions, the proposed method displayed good linear ranges (20.0-10000.0 ng L^-1), low limits of detection (5.6-10.3 ng L^-1), satisfactory precisions (1.1-6.8%) and recoveries (76.6-107.2%). Overall, the present work can be a versatile and worthy utility for the determination of PCA herbicides from different water samples.

Keywords: HPLC-MS/MS; Hexagonal boron nitride nanosheets; Magnetic solid-phase extraction; Phenoxy carboxylic acid herbicides; Water samples.