Isolated prostate amyloidosis; a case report

Urol Case Rep. 2022 Sep 16;45:102229. doi: 10.1016/j.eucr.2022.102229. eCollection 2022 Nov.


Identification of amyloidosis on a prostate biopsy specimen raises suspicion for systemic amyloidosis. For patients at risk of prostate adenocarcinoma, a transrectal MRI ultrasound fusion (MRI-TRUS) guided biopsy of the prostate is often needed for further investigation. Our patient is a 70 year old male presenting from his primary care provider with an elevated PSA. The patient underwent MRI-TRUS fusion biopsy of the prostate, which demonstrated AL (lambda)-type amyloidosis, confirmed by mass spectrometry in addition to prostatic adenocarcinoma. He was subsequently diagnosed with primary amyloidosis of the prostate without evidence of other amyloid deposition sites.

Keywords: Amyloidosis; Prostate amyloidosis; Prostate cancer.

Publication types

  • Case Reports