Microtubule cytoskeleton: Revealing new readers of the tubulin code

Linnea C Wethekam; Jeffrey K Moore

doi:10.1016/j.cub.2022.08.023

Microtubule cytoskeleton: Revealing new readers of the tubulin code

Curr Biol. 2022 Sep 26;32(18):R960-R962. doi: 10.1016/j.cub.2022.08.023.

Authors

Linnea C Wethekam¹, Jeffrey K Moore²

Affiliations

¹ Department of Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
² Department of Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: Jeffrey.moore@cuanschutz.edu.

PMID: 36167046
DOI: 10.1016/j.cub.2022.08.023

Abstract

Microtubule networks are thought to be controlled by an elaborate program of tubulin posttranslational modifications and proteins that selectively bind to modified states. A new study identifies proteins that bind tyrosinated tubulin, revealing a novel recognition mechanism.

Publication types

Comment

MeSH terms

Cytoskeleton / metabolism
Microtubules* / metabolism
Protein Processing, Post-Translational
Tubulin* / metabolism

Substances

Tubulin