The relationship between mean platelet volume and the mortality of patient severe head trauma; first study

Int J Neurosci. 2024 Jun;134(6):595-602. doi: 10.1080/00207454.2022.2130296. Epub 2022 Oct 7.


Background: Prediction of mortality in a patient with head trauma is essential. In this study, the effect of mean platelet volume (MPV) on the mortality rate of patients with severe head trauma was studied.

Material and methods: The relationship between mortality and mean platelet volumes of patient with cranial trauma was retrospectively analyzed.

Results: 43 patients with head trauma were admitted to the intensive care unit during the study period. While 17 patients died (Group I), 26 patients survived (Group II). Cox regression analysis showed that late MPV (at exitus or discharged date), WBC at admission, and age increase the mortality rate 1,770, 1,202, 1,052 times, respectively.

Conclusions: The present study shows that MPV may be a useful predictor of mortality in patients with severe head trauma.

Keywords: Mean platelet volume; head injury; intensive care unit; mortality.

MeSH terms

  • Adult
  • Aged
  • Craniocerebral Trauma* / blood
  • Craniocerebral Trauma* / mortality
  • Female
  • Humans
  • Male
  • Mean Platelet Volume*
  • Middle Aged
  • Retrospective Studies
  • Young Adult