Awakening dormant neurons long after spinal cord injury

PLoS Biol. 2022 Sep 29;20(9):e3001830. doi: 10.1371/journal.pbio.3001830. eCollection 2022 Sep.


Neurons lack the ability to regenerate after injury. A new Preregistered Article in PLOS Biology finds that pharmacologically boosting regenerative capacity long after injury in mice, together with an enriched animal environment, promotes axonal and synaptic plasticity.

Publication types

  • Comment

MeSH terms

  • Animals
  • Axons / physiology
  • Mice
  • Neuronal Plasticity / physiology
  • Neurons / physiology
  • Spinal Cord Injuries*
  • Spinal Cord*

Grant support

The author(s) received no specific funding for this work.