Diffusion-weighted magnetic resonance imaging for diagnosis of post-operative paediatric cholesteatoma

J Laryngol Otol. 2023 May;137(5):484-489. doi: 10.1017/S0022215122002055. Epub 2022 Oct 3.

Abstract

Objectives: High rates of recidivism are reported after paediatric cholesteatoma surgery. Our practice has adapted to include non-echoplanar diffusion-weighted magnetic resonance imaging for the diagnosis of residual or recurrent cholesteatoma. This audit aimed to evaluate the performance of non-echoplanar diffusion-weighted magnetic resonance imaging in our paediatric population.

Methods: A retrospective review was conducted of non-echoplanar diffusion-weighted magnetic resonance imaging scans performed to detect residual disease or recurrence after surgery for cholesteatoma in children from 1 January 2012 to 30 November 2017 in our centre. Follow-up diffusion-weighted magnetic resonance imaging scans were reviewed to 16 August 2019.

Results: Thirty-four diffusion-weighted magnetic resonance imaging scans were included. The sensitivity and specificity values of diffusion-weighted magnetic resonance imaging for detecting post-operative cholesteatoma were 81 per cent and 72 per cent, respectively. Positive predictive and negative predictive values were 72 per cent and 81 per cent, respectively.

Conclusion: Use of diffusion-weighted magnetic resonance imaging is recommended as a replacement for routine second-look surgical procedures in the paediatric population. However, we would caution that patients require close follow up after negative diffusion-weighted magnetic resonance imaging findings.

Keywords: Cholesteatoma; Diagnostic Imaging; Diffusion Magnetic Resonance Imaging; Mastoidectomy; Pediatrics.

MeSH terms

  • Child
  • Cholesteatoma, Middle Ear* / diagnostic imaging
  • Cholesteatoma, Middle Ear* / surgery
  • Diffusion Magnetic Resonance Imaging / methods
  • Humans
  • Magnetic Resonance Imaging
  • Neoplasm Recurrence, Local
  • Predictive Value of Tests
  • Prospective Studies
  • Sensitivity and Specificity