Ceftazidime-resistant Burkholderia pseudomallei masquerading as isolated atypical neuromelioidosis

Indian J Med Microbiol. 2023 Jan-Feb:41:111-113. doi: 10.1016/j.ijmmb.2022.09.006. Epub 2022 Oct 1.

Abstract

A middle-aged recently diagnosed uncontrolled diabetic from Mumbai, India presented with fever and headache for 8 weeks. Two weeks prior to his symptoms, he travelled to Lonavala during the monsoons and gave history of indoor swimming in a chlorinated pool. Investigations showed isolated neurological involvement with multiple brain abscesses. Abscess cultures grew a non-lactose fermenter. Automated systems failed to identify it. After assessment of his background history and detailed microbiological analysis of the organism, specific investigations were requested which confirmed the suspected diagnosis of melioidosis. We report an unusual presentation of ceftazidime-resistant Burkholderia pseumodmallei as isolated neuromelioidosis with brain abscesses.

Keywords: Burkholderia pseudomallei; Ceftazidime-resistance; Neuromelioidosis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Brain Abscess* / drug therapy
  • Burkholderia pseudomallei*
  • Ceftazidime
  • Humans
  • Male
  • Melioidosis* / diagnosis
  • Middle Aged
  • Trimethoprim, Sulfamethoxazole Drug Combination

Substances

  • Ceftazidime
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Anti-Bacterial Agents