Acute Coxsackievirus B3-induced meningo-cerebellitis in an immunocompetent adult patient

M Chung; L Andreoletti; Y N'Guyen; S Soize; F Bani-Sadr; M Hentzien

doi:10.1007/s13365-022-01098-9

Acute Coxsackievirus B3-induced meningo-cerebellitis in an immunocompetent adult patient

J Neurovirol. 2022 Dec;28(4-6):619-621. doi: 10.1007/s13365-022-01098-9. Epub 2022 Oct 4.

Authors

M Chung¹, L Andreoletti^{2

3}, Y N'Guyen^{1

3}, S Soize⁴, F Bani-Sadr^{5

6}, M Hentzien¹

Affiliations

¹ Service de Médecine Interne, Maladies Infectieuses, Immunologie Clinique, CHU de Reims, 51092 Cedex, Reims, France.
² Laboratoire de Virologie Médicale et Moléculaire, Pôle de Biologie et Biopathologie, CHU de Reims, Reims, France.
³ EA-4684 Cardio Vir, Faculté de Médecine de Reims, 51092 Cedex, Reims, France.
⁴ Service de Neuroradiologie, CHU de Reims, Reims, France.
⁵ Service de Médecine Interne, Maladies Infectieuses, Immunologie Clinique, CHU de Reims, 51092 Cedex, Reims, France. fbanisadr@chu-reims.fr.
⁶ EA-4684 Cardio Vir, Faculté de Médecine de Reims, 51092 Cedex, Reims, France. fbanisadr@chu-reims.fr.

PMID: 36194360
DOI: 10.1007/s13365-022-01098-9

Abstract

We report an acute Coxsackievirus B3 (CVB3)-induced meningo-cerebellitis in an immunocompetent adult patient. CVB3 has a global distribution and is the most common Enteroviruses cause of myocarditis and sudden cardiac death. To our knowledge, CVB3 is exceedingly rare as causes of meningo-encephalitis in immunocompetent adults, whereas some cases have been reported in neonates due to perinatal acquired infections or in immunocompromised patients.

Keywords: Coxsackievirus B3; Human enterovirus; Infectious encephalitis; Meningo-cerebellitis.

MeSH terms

Adult
Coxsackievirus Infections* / diagnosis
Enterovirus B, Human / genetics
Enterovirus Infections*
Enterovirus*
Humans
Infant, Newborn
Myocarditis* / drug therapy