Phytochemicals and Biological Activities of Burdock (Arctium lappa L.) Extracts: A Review

Chem Biodivers. 2022 Nov;19(11):e202200615. doi: 10.1002/cbdv.202200615. Epub 2022 Nov 3.


Arctium lappa L., also known as burdock, is an edible wild plant which has the ability to grow in distinct environments and is considered a weed in several parts of the world. This species has great value in the biological and medical fields with its major secondary components being phenolic compounds and terpenes, substances rich in desired biological activities as antioxidant, antimicrobial, antitumor and anti-inflammatory. In addition, burdock leaves extracts have shown a modulatory effect on the complement system, which plays an important role in the development of inflammatory diseases, with an inhibitory effect on all complement pathways. Thus, natural products with those relevant activities are promising agents for healthcare applications. Therefore, the species A. lappa may represent an interesting asset for researching and developing new therapies for inflammatory afflictions.

Keywords: Arctium lappa; alternative treatment; biological functions; complement system; extracts; popular medicinal herb; secondary metabolites.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / metabolism
  • Anti-Inflammatory Agents / pharmacology
  • Antioxidants / chemistry
  • Arctium* / chemistry
  • Phytochemicals / metabolism
  • Phytochemicals / pharmacology
  • Plant Extracts / chemistry


  • Plant Extracts
  • Antioxidants
  • Anti-Inflammatory Agents
  • Phytochemicals