A randomized control study of oxytocin augmentation of labour. 1. Obstetric outcome

Br J Obstet Gynaecol. 1987 Jun;94(6):512-7. doi: 10.1111/j.1471-0528.1987.tb03142.x.

Abstract

Sixty women who were progressing slowly in spontaneous labour were assigned at random to three management protocols. Group 1 were observed without the use of oxytocin for 8 h while groups 2 and 3 were managed with a low-dose and high-dose oxytocin protocol respectively. The caesarean section rates were not significantly different between the three groups: 45%, 35% and 26% respectively. Cervical dilatation rate increased significantly after oxytocin infusion in both treatment groups compared with controls. The 'delay-to-delivery' interval and second stage duration were significantly shorter in the high-dose group than in the control group. There were no measurable differences in the condition of the newborn infants between the three groups.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cervix Uteri / drug effects
  • Cesarean Section
  • Female
  • Humans
  • Infant, Newborn
  • Labor, Induced*
  • Labor, Obstetric / physiology*
  • Oxytocin / administration & dosage*
  • Patient Acceptance of Health Care
  • Pilot Projects
  • Pregnancy
  • Prognosis
  • Random Allocation

Substances

  • Oxytocin