[Progress in platelets and chronic obstructive pulmonary disease]

Zhonghua Jie He He Hu Xi Za Zhi. 2022 Oct 12;45(10):1050-1054. doi: 10.3760/cma.j.cn112147-20220425-00349.
[Article in Chinese]

Abstract

Platelets-related pathophysiological mechanism and clinical research is one of the research hot topics in chronic obstructive pulmonary disease (COPD) at home and abroad. Increasing evidence has proved the association between thrombocytosis and COPD. Platelets activation interacts with COPD. Antiplatelet therapy has been shown to have significant effects on both short-term and long-term outcomes in COPD. Platelets inhibition may be an emerging therapeutic target for COPD, and antiplatelet therapy is expected to become an inexpensive and effective treatment for COPD. This article reviewed the research progress in platelets and COPD.

血小板相关病理生理机制及临床研究是目前国内外慢性阻塞性肺疾病(慢阻肺)的研究热点之一,越来越多证据证明血小板增多症与慢阻肺有关,血小板活化与慢阻肺相互影响。抗血小板治疗被证实对慢阻肺短期和长期结局都有明显影响。血小板抑制可能成为慢阻肺新的治疗靶点,抗血小板治疗有望成为慢阻肺经济而有效的治疗方式。本文就血小板与慢阻肺相关研究进展作一综述。.

Publication types

  • Review

MeSH terms

  • Blood Platelets*
  • Humans
  • Platelet Aggregation Inhibitors / pharmacology
  • Platelet Aggregation Inhibitors / therapeutic use
  • Pulmonary Disease, Chronic Obstructive* / drug therapy

Substances

  • Platelet Aggregation Inhibitors