Histochemical changes in rat sperm malate dehydrogenase activity during passage through epididymis

Endocrinol Jpn. 1987 Apr;34(2):231-5. doi: 10.1507/endocrj1954.34.231.


Histochemical activity of malate dehydrogenase (MDH: E.C. in rat sperm mitochondria decreased during the epididymal transit of sperm. In an electrophoretic study two major MDH isozymes (MDH-A and MDH-B) were demonstrated in the sperm. The epididymal sperm showed two minor isozymes associated with MDH-A, while the testicular sperm did not.

MeSH terms

  • Animals
  • Epididymis*
  • Histocytochemistry
  • Isoenzymes / analysis
  • Malate Dehydrogenase / analysis*
  • Male
  • Rats
  • Rats, Inbred Strains
  • Sperm Transport*
  • Spermatozoa / enzymology*


  • Isoenzymes
  • Malate Dehydrogenase